Document Detail


Small vessel occlusion in acute acalculous cholecystitis.
MedLine Citation:
PMID:  1736386     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ischemia is one mechanism implicated in the pathogenesis of acute acalculous cholecystitis. Gallbladder specimen arteriography was performed to define the comparative status of cystic artery runoff in the macroscopically normal gallbladder (n = 10), in acute gallstone-associated cholecystitis (n = 10), and in acute acalculous cholecystitis (n = 7). Standardized film exposure and quantity of contrast medium administered permitted objective intergroup comparison. Compared to the macroscopically normal gallbladder, specimens of acute gallstone-associated cholecystitis exhibited arterial dilatation and extensive venous filling. In contrast, multiple arterial occlusions, with absent or minimal venous filling, were consistent features of acute acalculous cholecystitis; the degree of arteriographic abnormality for acute acalculous cholecystitis corresponded to the severity of gallbladder pathologic findings. Small vessel occlusion, on the basis of low splanchnic flow or intravascular coagulation, may be a fundamental element in the pathogenesis of acute acalculous cholecystitis.
Authors:
B L Warren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery     Volume:  111     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-03-11     Completed Date:  1992-03-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  163-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Surgery, Tygerberg Hospital/University of Stellenbosch, South Africa.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Angiography
Arterial Occlusive Diseases / complications*
Calculi
Cholecystitis / complications,  etiology*
Cholecystography
Cholelithiasis / complications
Female
Gallbladder / blood supply*
Humans
Ischemia / complications
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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