Document Detail


Small vessel disease of the heart resulting in myocardial necrosis and death despite angiographically normal coronary arteries.
MedLine Citation:
PMID:  377934     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 46 year old man who had undergone cardiac transplantation 1 year previously had progressive congestive heart failure without evidence of cardiac rejection. Cardiac catheterization and angiography revealed a reduced ejection fraction and cardiac output caused by diffuse left ventricular hypokinesia, but the epicardial coronary arteries were widely patent. The transit time of injected contrast material across the coronary arterial tree was greatly slowed. Within a few days cardiogenic shock and death occurred. The large epicardial coronary vessels were grossly patent at autopsy, although nonstenosing arteriosclerotic plaques were identifiable histologically. However, intramyocardial vessels showed severe arteriosclerotic narrowing, resulting in multiple, diffuse microinfarcts.
Authors:
J W Mason; A Strefling
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  44     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1979 Jul 
Date Detail:
Created Date:  1979-08-29     Completed Date:  1979-08-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  171-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Coronary Angiography
Coronary Disease / pathology*,  physiopathology,  radiography
Coronary Vessels / pathology*
Electrocardiography
Heart Conduction System / physiopathology
Heart Failure / etiology
Heart Transplantation*
Humans
Male
Middle Aged
Myocardial Infarction / pathology*
Myocardium / pathology*
Necrosis
Transplantation, Homologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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