| Small vessel avulsion and acute aortic syndrome: a putative aetiology for initiation and propagation of blunt traumatic aortic injury at the isthmus. | |
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MedLine Citation:
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PMID: 17196753 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Based on literature, clinical observation and the analysis of material properties of the aorta, we hypothesize that the aortic isthmus is intrinsically susceptible to blunt trauma because it has a higher density of tributary vessels than other elements of the aortic tree, the avulsion of which during trauma, is a contributory factor in the development of an acute aortic syndrome resulting from intra-mural haematoma, localized dissection and ultimately rupture. This hypothesis provides putative explanations for several aspects of the injury profile including: localized peri-isthmus injuries, inside out injury profiles and the concept of initiation versus propagation of blunt traumatic aortic injury. |
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Authors:
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Mark L Field; Priya Sastry; Aihong Rachel Zhao; David Richens |
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Publication Detail:
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Type: Journal Article Date: 2006-12-29 |
Journal Detail:
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Title: Medical hypotheses Volume: 68 ISSN: 0306-9877 ISO Abbreviation: Med. Hypotheses Publication Date: 2007 |
Date Detail:
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Created Date: 2007-04-03 Completed Date: 2007-07-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: Scotland |
Other Details:
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Languages: eng Pagination: 1392-8 Citation Subset: IM |
Affiliation:
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The Cardiothoracic Centre, Thomas Drive, Liverpool L14 3PE, UK. mlfield@doctors.net.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aorta / injuries*, pathology Aortic Rupture / etiology, pathology* Humans Models, Cardiovascular* Syndrome Wounds, Nonpenetrating / etiology*, pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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