Document Detail

Small vessel avulsion and acute aortic syndrome: a putative aetiology for initiation and propagation of blunt traumatic aortic injury at the isthmus.
MedLine Citation:
PMID:  17196753     Owner:  NLM     Status:  MEDLINE    
Based on literature, clinical observation and the analysis of material properties of the aorta, we hypothesize that the aortic isthmus is intrinsically susceptible to blunt trauma because it has a higher density of tributary vessels than other elements of the aortic tree, the avulsion of which during trauma, is a contributory factor in the development of an acute aortic syndrome resulting from intra-mural haematoma, localized dissection and ultimately rupture. This hypothesis provides putative explanations for several aspects of the injury profile including: localized peri-isthmus injuries, inside out injury profiles and the concept of initiation versus propagation of blunt traumatic aortic injury.
Mark L Field; Priya Sastry; Aihong Rachel Zhao; David Richens
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Publication Detail:
Type:  Journal Article     Date:  2006-12-29
Journal Detail:
Title:  Medical hypotheses     Volume:  68     ISSN:  0306-9877     ISO Abbreviation:  Med. Hypotheses     Publication Date:  2007  
Date Detail:
Created Date:  2007-04-03     Completed Date:  2007-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505668     Medline TA:  Med Hypotheses     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  1392-8     Citation Subset:  IM    
The Cardiothoracic Centre, Thomas Drive, Liverpool L14 3PE, UK.
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MeSH Terms
Acute Disease
Aorta / injuries*,  pathology
Aortic Rupture / etiology,  pathology*
Models, Cardiovascular*
Wounds, Nonpenetrating / etiology*,  pathology*

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