| Small temporal pole encephaloceles: a treatable cause of "lesion negative" temporal lobe epilepsy. | |
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MedLine Citation:
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PMID: 20384762 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Epilepsy due to encephaloceles of the temporal pole may be an under recognized, treatable cause of refractory temporal lobe epilepsy (TLE). We describe three adult patients initially labeled "lesion negative" TLE. In all, video–electroencephalography (EEG) revealed ictal theta in the left temporal region and positron emission tomography (PET) showed temporal lobe hypometabolism, but neuropsychology revealed preserved verbal memory. Close inspection of structural magnetic resonance imaging (MRI) suggested subtle abnormalities at the tip of the left temporal lobe. High resolution computed tomography (CT) confirmed bony defects in the inner table of the skull. 3T MRI with fine coronal and sagittal slices indicated cerebrospinal fluid (CSF) and brain tissue protruding into the defects. All proceeded to resection of the temporal tip and became seizure free. Patients with "lesion negative" TLE should have careful review of images covering the temporal pole. If encephalocele is suspected, further imaging with high-resolution CT and MRI can be helpful. Temporal polar resection, sparing mesial structures, appears to be curative. |
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Authors:
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Amal Abou-Hamden; Mandy Lau; Gavin Fabinyi; Samuel F Berkovic; Graeme D Jackson; L Anne Mitchell; Renate Kalnins; Greg Fitt; John S Archer |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Epilepsia Volume: 51 ISSN: 1528-1167 ISO Abbreviation: Epilepsia Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-10 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 2199-202 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Austin Health, Melbourne, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Electroencephalography Encephalocele / complications*, diagnosis*, surgery Epilepsy, Temporal Lobe / diagnosis*, etiology*, surgery Female Fluorodeoxyglucose F18 / diagnostic use Humans Magnetic Resonance Imaging Male Positron-Emission Tomography Temporal Lobe / radionuclide imaging, surgery Video Recording |
| Chemical | |
Reg. No./Substance:
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63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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