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Small lymphocytic lymphoma in a patient with CREST syndrome.
MedLine Citation:
PMID:  21982887     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We report a case of a 61-year-old man with a history of CREST syndrome (calcinosis cutis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) who presented for evaluation of thrombocytopenia. He had evident cervical adenopathy and lymph node biopsy showed small lymphocytic lymphoma (SLL) with evident systemic adenopathy and bone marrow involvement. The patient achieved a complete remission with FCR (fludarabine/cyclophosphamide/rituximab) chemotherapy. About 30 cases of lymphomas are reported in the literature in association with systemic sclerosis. To our knowledge, there are no reports of a small lymphocytic lymphoma (SLL) in association with limited cutaneous systemic sclerosis with classic features of the CREST syndrome.
Authors:
B M William; T Harbert; A K Ganti; P J Bierman
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Hematology/oncology and stem cell therapy     Volume:  4     ISSN:  1658-3876     ISO Abbreviation:  -     Publication Date:    2011 Third Quarter
Date Detail:
Created Date:  2011-10-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101468532     Medline TA:  Hematol Oncol Stem Cell Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  132-135     Citation Subset:  -    
Affiliation:
University of Nebraska Medical Center and Omaha Veterans Affairs Medical Center, Omaha, Nebraska, USA bwillia@unmc.edu.
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