| Small-intestinal and colonic changes after biliopancreatic bypass for morbid obesity. | |
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MedLine Citation:
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PMID: 3101167 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Morphologic and functional adaptations of the functioning intestine were evaluated in 41 patients before and after biliopancreatic bypass for morbid obesity. This surgical procedure diverts pancreatobiliary secretions via the duodenum and the jejunum into the colon, the remaining small intestine being anastomosed to the stomach after antrectomy. In the proximal ileum there was an 80% increase of the height of villi; the specific activities of maltase, sucrase, and aminopeptidase in brush border membranes remained unaffected, and that of lactase tended to decrease. In the distal ileum villi heights increased only by 58%, and disaccharidase activities (except for maltase) were slightly enhanced. In the colon the mucosa displayed, in some patients, focal appearance of true villi, and brush border enzyme activities increased concomitantly. We conclude that biliopancreatic bypass induces an adaptation of all intestinal segments of the functioning intestine; this adaptation tends to compensate for the shortening of the gut continuity. |
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Authors:
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C Stock-Damgé; M Aprahamian; F Raul; J Marescaux; N Scopinaro |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of gastroenterology Volume: 21 ISSN: 0036-5521 ISO Abbreviation: Scand. J. Gastroenterol. Publication Date: 1986 Nov |
Date Detail:
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Created Date: 1987-03-10 Completed Date: 1987-03-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0060105 Medline TA: Scand J Gastroenterol Country: NORWAY |
Other Details:
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Languages: eng Pagination: 1115-23 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biliary Tract / metabolism, pathology Biliary Tract Surgical Procedures* Colon / pathology* Female Humans Intestine, Small / pathology* Male Middle Aged Obesity, Morbid / therapy* Pancreas / metabolism, pathology, surgery* |
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