| Small intestinal bacterial overgrowth. | |
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MedLine Citation:
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PMID: 20937459 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Despite the current increase in interest in the role of the microbiota in health and disease and the recognition, for over 50 years, that an excess of colonic-type flora in the small intestine could lead to a malabsorption syndrome, small intestinal overgrowth remains poorly defined. This lack of clarity owes much to the difficulties that arise in attempting to arrive at consensus with regard to the diagnosis of this condition: there is currently no gold standard and the commonly available methodologies (the culture of jejunal aspirates and a variety of breath tests) suffer from considerable variations in their performance and interpretation, leading to variations in the prevalence of overgrowth in a variety of clinical contexts. Treatment is similarly supported by a scant evidence base and the most commonly used antibiotic regimens owe more to custom than clinical trials. |
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Authors:
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Eamonn M M Quigley; Ahmed Abu-Shanab |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Infectious disease clinics of North America Volume: 24 ISSN: 1557-9824 ISO Abbreviation: Infect. Dis. Clin. North Am. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-10-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804508 Medline TA: Infect Dis Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 943-59, viii-ix Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland. e.quigley@ucc.ie |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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