Document Detail

Small changes in nutrition and physical activity promote weight loss and maintenance: 3-month evidence from the ASPIRE randomized trial.
MedLine Citation:
PMID:  18568379     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Current obesity interventions use intensive behavior changes to achieve large initial weight loss. However, weight regain after treatment is common, and drop out rates are relatively high. Smaller behavioral changes could produce initial weight loss and be easier to sustain after active treatment. PURPOSE: We examined the efficacy of an intervention that targeted small but cumulative participant-chosen changes in diet and physical activity (ASPIRE) and compared this treatment to standard didactic and wait-list control groups. The primary outcome measures were body weight, waist circumference, and intra-abdominal fat. METHODS: Fifty-nine overweight or obese sedentary adults were randomized to one of three groups: (1) the ASPIRE group (n = 20), (2) a standard educationally-based treatment group (n = 20), or (3) a wait list control group (n = 19) for 4 months. Active treatment groups received identical resistance and aerobic training programs. RESULTS: Intention-to-treat analyses showed that participants in the ASPIRE group lost significantly more weight than the standard and control groups (-4.4 vs. -1.1 and +0.1 kg, respectively), and the greater initial weight loss in the ASPIRE group was sustained 3 months after active treatment (4.1 kg). An alternative analytic strategy (0.3 kg/month weight gain for those lost to follow-up) showed continued weight loss (-0.2 kg after active treatment; -4.6 kg from baseline) at follow-up in the ASPIRE group. Similar patterns were observed for the other adiposity measures. CONCLUSION: More modest behavioral changes are capable of promoting weight loss, decreasing adiposity markers and sustaining these changes over 3 months. Longer-term studies comparing this approach with traditional behavioral weight loss treatments are warranted.
Lesley D Lutes; Richard A Winett; Steven D Barger; Janet R Wojcik; William G Herbert; Sharon M Nickols-Richardson; Eileen S Anderson
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2008-06-21
Journal Detail:
Title:  Annals of behavioral medicine : a publication of the Society of Behavioral Medicine     Volume:  35     ISSN:  1532-4796     ISO Abbreviation:  Ann Behav Med     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-08-18     Completed Date:  2008-10-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510246     Medline TA:  Ann Behav Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  351-7     Citation Subset:  IM    
Department of Psychology, East Carolina University, 104 Rawl, East Fifth Street, Greenville, NC 27858-4353, USA.
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MeSH Terms
Behavior Therapy
Decision Making
Diet, Reducing
Intervention Studies
Middle Aged
Motor Activity*
Obesity / diet therapy*,  prevention & control
Patient Education as Topic
Personal Autonomy*
Treatment Outcome
Weight Loss*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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