| Small cell neuroendocrine carcinoma of the urinary bladder: report on two cases and review of the literature. | |
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MedLine Citation:
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PMID: 20549899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Small cell (Neuroendocrine) carcinoma of the urinary bladder is a rare but highly aggressive malignancy. The neoplastic cells exhibit both neuroendocrine and epithelial differentiation. It is morphologically indistinguishable from the more common pulmonary small cell carcinoma. It can occur either in association with urothelial (transitional cell) carcinoma or in a pure form. Presenting signs and symptoms are non specific. Histologically, it can mimic poorly differentiated urothelial carcinoma and lymphoma. Muscle invasion is almost invariably present at diagnosis and mortality is mainly due to metastases rather than loco regional recurrence. The optimal therapeutic modality is still controversial. In this article, we report on two cases occurring in a pure form and we briefly review the published literature regarding the clinical presentation, morphology, differential diagnosis, prognosis and treatment. |
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Authors:
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Camil J Chouairy; Ali N Salloum; George Y Ghazal |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Le Journal médical libanais. The Lebanese medical journal Volume: 58 ISSN: 0023-9852 ISO Abbreviation: J Med Liban Publication Date: 2010 Apr-Jun |
Date Detail:
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Created Date: 2010-06-16 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375352 Medline TA: J Med Liban Country: Lebanon |
Other Details:
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Languages: eng Pagination: 111-9 Citation Subset: IM |
Affiliation:
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Department of Pathology, St George Hospital University Medical Center, Achrafieh, Beirut, Lebanon. camil.chouairy@balamand.edu.lb |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Carcinoma, Neuroendocrine / pathology*, surgery Cystoscopy Humans Male Urinary Bladder Neoplasms / pathology*, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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