| Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBS. | |
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MedLine Citation:
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PMID: 18377795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Small bowel bacterial overgrowth (SBBO) is common in infants and children with short bowel syndrome (SBS). Its occurrence is due to alterations in anatomy, motility, and secretion, which promote the abnormal growth of bacteria. SBBO is associated with significant clinical problems, including prolonged dependence on parenteral nutrition, liver injury, and malabsorption. A major clinical challenge is in making the correct diagnosis of bacterial overgrowth. Management of this disorder is still poorly understood and should be evaluated adequately. This review addresses the current understanding of bacteria in the intestines and issues related to bacterial overgrowth in pediatric SBS. |
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Authors:
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Conrad R Cole; Thomas R Ziegler |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Current gastroenterology reports Volume: 9 ISSN: 1534-312X ISO Abbreviation: Curr Gastroenterol Rep Publication Date: 2007 Dec |
Date Detail:
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Created Date: 2008-04-01 Completed Date: 2008-05-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888896 Medline TA: Curr Gastroenterol Rep Country: United States |
Other Details:
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Languages: eng Pagination: 456-62 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Drive, Atlanta, GA 30322, USA. Conrad_cole@oz.ped.emory.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological Anti-Bacterial Agents / administration & dosage Blind Loop Syndrome / diagnosis, epidemiology*, therapy Breath Tests Child Colony Count, Microbial Comorbidity Digestive System Surgical Procedures Enteral Nutrition Humans Intestinal Absorption / physiology Intestinal Mucosa / pathology Intestine, Small / immunology, microbiology*, physiopathology Liver Diseases / epidemiology Probiotics / administration & dosage, therapeutic use Risk Factors Short Bowel Syndrome / diagnosis, epidemiology*, etiology, microbiology, physiopathology, surgery |
| Grant Support | |
ID/Acronym/Agency:
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K12RR17643/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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