| A Small Molecule Promotes Mitochondrial Fusion in Mammalian Cells. | |
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MedLine Citation:
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PMID: 22907892 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Mitochondrial dynamics: An image-based screen identified a small molecule, M1, that specifically promotes the fusion of fragmented mitochondria and protects cells from mitochondrial-fragmentation-associated cell death. Mechanistic studies revealed that M1 shifts the mitochondrial dynamic balance towards fusion. |
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Authors:
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Danling Wang; Jianing Wang; Ghislain M C Bonamy; Shelly Meeusen; Richard G Brusch; Carolina Turk; Pengyu Yang; Peter G Schultz |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-21 |
Journal Detail:
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Title: Angewandte Chemie (International ed. in English) Volume: - ISSN: 1521-3773 ISO Abbreviation: Angew. Chem. Int. Ed. Engl. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370543 Medline TA: Angew Chem Int Ed Engl Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Department of Chemistry, the Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037 (USA) http://schultz.scripps.edu/ |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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