| Small Bowel Ischemia. | |
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MedLine Citation:
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PMID: 11177681 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Small bowel ischemia is a relatively uncommon disorder requiring prompt recognition and aggressive management if significant morbidity and mortality are to be averted. The pathophysiology of the ischemic event usually will determine the management approach used. Factors to be considered include whether the ischemia is the consequence of arterial or venous occlusive disease; the cause and nature of the ischemia (ie, a consequence of arterial spasm, inflammation, complete or incomplete occlusion); whether the occlusion is the result of an embolus or thrombosis; the preexistence and degree of development of arterial collateral channels; and the existence and extent of comorbid conditions. Established and experimental therapeutic interventions have varied in efficacy and include 1) correction of physiologic alterations predisposing to the ischemic event, 2) angiography with arterial infusion of vasodilators; 3) embolectomy or thrombectomy, and resection of necrotic bowel; 4) anticoagulation (veno-occlusive disease); and 5) selective application of thrombolytic agents. The overall success of any therapeutic intervention depends upon the early recognition and management of ischemia, as the incidence of morbidity and mortality rises after infarction occurs. |
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Authors:
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Omar S. Nehme; Arvey I. Rogers |
Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Current treatment options in gastroenterology Volume: 4 ISSN: 1534-309X ISO Abbreviation: Curr Treat Options Gastroenterol Publication Date: 2001 Feb |
Date Detail:
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Created Date: 2001-Feb-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815941 Medline TA: Curr Treat Options Gastroenterol Country: - |
Other Details:
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Languages: ENG Pagination: 51-56 Citation Subset: - |
Affiliation:
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Division of Gastroenterology, University of Miami School of Medicine, 1611 Northwestern 12th Avenue, Miami, FL 33136, USA. |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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