Document Detail

Slow-release devices for fluoride delivery to high-risk individuals.
MedLine Citation:
PMID:  11359050     Owner:  NLM     Status:  MEDLINE    
The latest fluoride research is investigating the use of slow-release devices for the long-term intra-oral provision of fluoride. 174 children aged 8 years with fluoride slow-releasing glass devices were shown to develop 67% fewer new carious teeth and 76% fewer new carious surfaces in a 2-year double-blind caries study. There were 55% fewer new occlusal fissure carious cavities showing that occlusal surfaces were also protected by the fluoride released from the devices. The fluoride devices release low levels of fluoride for at least 2 years and have great potential for use in preventing dental caries in high-caries-risk groups and irregular dental attenders in addition to a number of other applications.
K J Toumba
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Caries research     Volume:  35 Suppl 1     ISSN:  0008-6568     ISO Abbreviation:  Caries Res.     Publication Date:  2001  
Date Detail:
Created Date:  2001-05-18     Completed Date:  2001-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0103374     Medline TA:  Caries Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  10-3     Citation Subset:  D; IM    
Department of Paediatric Dentistry, Leeds Dental Institute, Leeds, UK.
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MeSH Terms
Biocompatible Materials
Cariostatic Agents / administration & dosage*
Delayed-Action Preparations
Dental Caries / prevention & control
Dental Caries Susceptibility*
Double-Blind Method
Drug Delivery Systems*
Fluorides / administration & dosage*
Follow-Up Studies
Membranes, Artificial
Risk Factors
Reg. No./Substance:
0/Biocompatible Materials; 0/Cariostatic Agents; 0/Delayed-Action Preparations; 0/Fluorides; 0/Membranes, Artificial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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