Document Detail


Sleeve lobectomy as an alternative procedure to pneumonectomy for non-small cell lung cancer.
MedLine Citation:
PMID:  20104190     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: The aim of this study is to compare the outcomes of sleeve lobectomy (SL) and pneumonectomy (PN) and to determine which one is more acceptable standard procedure for patients with non-small cell lung cancer. METHODS: From 1996 to 2005, 424 patients underwent SL (n = 157) and PN (n = 267) in our institution. Propensity score matching analysis was performed to compare these two groups for mortality, morbidity, survival, recurrence, and postoperative pulmonary function. RESULTS: In each group, 105 patients were eligible for analysis. The operative mortality was lower in the SL group (1.0%) than the PN group (8.6%), (p < 0.0001). The morbidity was similar (33.4% versus 29.5%, p = 0.376). The 5-year survival was lower in the PN group (PN, 32.14% versus SL, 58.43%, p = 0.0002). The recurrence pattern (locoregional versus distant) did not differ between two groups (p = 0.180). The mean actual postoperative first second forced expiratory volume in the patients underwent SL was 2.05 +/- 0.55 liter, which increased by 7.9% compared with the predicted-postoperative first second forced expiratory volume. CONCLUSIONS: Our results showed that the SL can be performed with low operative risk and may offer superior survival and better postoperative pulmonary function compared with the PN in selected patients. If anatomically feasible, a SL must be considered as a favorable alternative to PN in patients with non-small cell lung cancer.
Authors:
Joon Suk Park; Hee Chul Yang; Hong Kwan Kim; Kwhanmien Kim; Young Mog Shim; Yong Soo Choi; Jhingook Kim
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer     Volume:  5     ISSN:  1556-1380     ISO Abbreviation:  J Thorac Oncol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-01     Completed Date:  2010-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101274235     Medline TA:  J Thorac Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  517-20     Citation Subset:  IM    
Affiliation:
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / pathology,  surgery*
Carcinoma, Large Cell / pathology,  surgery*
Carcinoma, Non-Small-Cell Lung / pathology,  surgery*
Carcinoma, Squamous Cell / pathology,  surgery*
Female
Follow-Up Studies
Humans
Lung Neoplasms / pathology,  surgery*
Male
Middle Aged
Morbidity
Neoplasm Recurrence, Local / pathology,  surgery
Neoplasm Staging
Pneumonectomy*
Postoperative Period
Propensity Score
Pulmonary Artery / surgery*
Retrospective Studies
Survival Rate
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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