| Sleeve lobectomy as an alternative procedure to pneumonectomy for non-small cell lung cancer. | |
| | |
MedLine Citation:
|
PMID: 20104190 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: The aim of this study is to compare the outcomes of sleeve lobectomy (SL) and pneumonectomy (PN) and to determine which one is more acceptable standard procedure for patients with non-small cell lung cancer. METHODS: From 1996 to 2005, 424 patients underwent SL (n = 157) and PN (n = 267) in our institution. Propensity score matching analysis was performed to compare these two groups for mortality, morbidity, survival, recurrence, and postoperative pulmonary function. RESULTS: In each group, 105 patients were eligible for analysis. The operative mortality was lower in the SL group (1.0%) than the PN group (8.6%), (p < 0.0001). The morbidity was similar (33.4% versus 29.5%, p = 0.376). The 5-year survival was lower in the PN group (PN, 32.14% versus SL, 58.43%, p = 0.0002). The recurrence pattern (locoregional versus distant) did not differ between two groups (p = 0.180). The mean actual postoperative first second forced expiratory volume in the patients underwent SL was 2.05 +/- 0.55 liter, which increased by 7.9% compared with the predicted-postoperative first second forced expiratory volume. CONCLUSIONS: Our results showed that the SL can be performed with low operative risk and may offer superior survival and better postoperative pulmonary function compared with the PN in selected patients. If anatomically feasible, a SL must be considered as a favorable alternative to PN in patients with non-small cell lung cancer. |
| | |
Authors:
|
Joon Suk Park; Hee Chul Yang; Hong Kwan Kim; Kwhanmien Kim; Young Mog Shim; Yong Soo Choi; Jhingook Kim |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Volume: 5 ISSN: 1556-1380 ISO Abbreviation: J Thorac Oncol Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-04-01 Completed Date: 2010-07-22 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101274235 Medline TA: J Thorac Oncol Country: United States |
Other Details:
|
Languages: eng Pagination: 517-20 Citation Subset: IM |
Affiliation:
|
Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenocarcinoma
/
pathology,
surgery* Carcinoma, Large Cell / pathology, surgery* Carcinoma, Non-Small-Cell Lung / pathology, surgery* Carcinoma, Squamous Cell / pathology, surgery* Female Follow-Up Studies Humans Lung Neoplasms / pathology, surgery* Male Middle Aged Morbidity Neoplasm Recurrence, Local / pathology, surgery Neoplasm Staging Pneumonectomy* Postoperative Period Propensity Score Pulmonary Artery / surgery* Retrospective Studies Survival Rate Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparative vascular and renal tubular effects of angiotensin II receptor blockers combined with a t...
Next Document: Second-Line Therapy for Elderly Patients with Non-small Cell Lung Cancer Who Failed Previous Chemoth...