Document Detail

Sleep patterns in patients with late onset partial epilepsy receiving chronic carbamazepine (CBZ) therapy.
MedLine Citation:
PMID:  2127255     Owner:  NLM     Status:  MEDLINE    
A night-time polygraphic sleep recording was performed in 14 patients with late onset partial epilepsy receiving chronic carbamazepine monotherapy. All patients had unstable nocturnal sleep patterns as indicated by significantly altered sleep continuity parameters compared with normal controls. Patients with poor seizure control tended to show greater alterations of sleep stability compared to patients in complete clinical remission but the difference failed to reach statistical significance. Epileptic patients also showed less REM sleep and longer REM latencies compared with normal controls, the most altered REM values being observed in patients with poor seizure control. These data confirm that polygraphic sleep alterations are seen in patients with symptomatic focal epilepsy and indicate that these abnormalities occur irrespective of seizure recurrence.
R Manni; C A Galimberti; C Zucca; L Parietti; A Tartara
Related Documents :
11827645 - Sleep and epilepsy.
1928615 - Circadian rhythm of regular spike-wave discharges in childhood absence epilepsy.
9637605 - Predictive value of interictal epileptiform discharges during non-rem sleep on scalp ee...
8825265 - Contribution to the genetics of symptomatic generalized tonic-clonic seizures: waking a...
1478115 - Age-variant and age-invariant rhythmicities in the cortical and hippocampal electrical ...
24188035 - Reciprocal relations between children's sleep and their adjustment over time.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Epilepsy research     Volume:  7     ISSN:  0920-1211     ISO Abbreviation:  Epilepsy Res.     Publication Date:    1990 Sep-Oct
Date Detail:
Created Date:  1991-04-08     Completed Date:  1991-04-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8703089     Medline TA:  Epilepsy Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  72-6     Citation Subset:  IM    
Institute of Neurology C. Mondino, University of Pavia, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Carbamazepine / therapeutic use*
Epilepsies, Partial / drug therapy,  physiopathology*
Sleep / physiology*
Sleep Stages
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The role of LH in the autofeedback inhibition of LH and FSH secretion in ovariectomized rats.
Next Document:  Expression of Tau protein and Tau mRNA in the cerebellum during axonal outgrowth.