Document Detail

Sleep and epilepsy.
MedLine Citation:
PMID:  10987575     Owner:  NLM     Status:  MEDLINE    
Sleep disturbance in patients with epilepsy is frequently overlooked, but may contribute to decreased daytime functioning and increased seizure activity. Although complicated, the relationship between sleep and epilepsy is becoming clearer. Sleep, and particularly deep non-rapid-eye-movement sleep, increase interictal epileptiform activity. Sleep increases certain seizure types and the rate of generalization of partial seizures, however rapid-eye-movement sleep seems to suppress seizures. Sleep disorders, particularly sleep apnea, exacerbate seizures. Seizures, in turn, can disrupt sleep structure, particularly rapid-eye-movement sleep. An understanding of these relationships is important in seizure control and in maximizing the quality of life for patients with epilepsy.
C W Bazil
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in neurology     Volume:  13     ISSN:  1350-7540     ISO Abbreviation:  Curr. Opin. Neurol.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-12-11     Completed Date:  2000-12-22     Revised Date:  2013-01-18    
Medline Journal Info:
Nlm Unique ID:  9319162     Medline TA:  Curr Opin Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  171-5     Citation Subset:  IM    
Comprehensive Epilepsy Center, The Neurological Institute of Columbia University, New York, NY 10032, USA.
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MeSH Terms
Anticonvulsants / therapeutic use
Epilepsy / complications,  drug therapy,  physiopathology*
Sleep Deprivation / physiopathology
Sleep Disorders / etiology
Sleep Stages / drug effects
Reg. No./Substance:

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