Document Detail

Skin test reactivity to molds in pre-school children with newly diagnosed asthma.
MedLine Citation:
PMID:  17168977     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The aim of the present study was to evaluate the prevalence of sensitization to molds and to house dust mites (HDM) in pre-school children with newly-diagnosed asthma. METHODS: From 1996 to 2000, 122 children 1 to 6 years of age with fresh asthma treated in the Kuopio University Hospital, Kuopio, Finland, were recruited in the study; 94% attended. Skin prick tests were performed to common inhalant allergens and to 10 molds. The homes were surveyed for moisture damage. RESULTS: A majority of the houses had signs of dampness and moisture. One-third of the children reacted to inhalant allergens. There were 11 positive reactions to molds in five children who all reacted to at least one animal dander or seasonal pollen. Aspergillus fumigatus, Botrytis cinerea, and Cladosporium herbarum were the most common mold allergens. There were only two children with positive reactions to HDM, and none of them reacted to molds. No associations were found between the presence or degree of moisture problems at home and mold or HDM allergy. CONCLUSION: Sensitization to molds seems to play only a minor role in pre-school children with newly-diagnosed asthma in a northern climate where the incidences of mold and HDM allergies are rather low.
Kaj Korhonen; Saara Mähönen; Anne Hyvärinen; Aino Nevalainen; Tuula Husman; Juha Pekkanen; Matti Korppi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics international : official journal of the Japan Pediatric Society     Volume:  48     ISSN:  1328-8067     ISO Abbreviation:  Pediatr Int     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-15     Completed Date:  2007-01-24     Revised Date:  2008-05-21    
Medline Journal Info:
Nlm Unique ID:  100886002     Medline TA:  Pediatr Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  577-81     Citation Subset:  IM    
Department of Paediatrics, Kuopio University Hospital, Kuopio, Finland.
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MeSH Terms
Age Factors
Asthma / diagnosis,  epidemiology,  immunology*
Child, Preschool
Finland / epidemiology
Fungi / immunology*
Prospective Studies
Pyroglyphidae / immunology
Skin Tests*

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