Document Detail

Skin and soft tissue polymicrobial infections from intravenous abuse of drugs.
MedLine Citation:
PMID:  425502     Owner:  NLM     Status:  MEDLINE    
Skin and soft tissue infections were studied in 21 seriously ill narcotic addicts who had been admitted to hospital. Subcutaneous abscesses were present in 14 patients; cellulitis was noted in 3, pyomyositis in 2 and necrotizing fasciitis in 2. In four patients there was septicemia. Infections in 14 patients (66.6 percent) were associated with anaerobic bacteria, which were the exclusive isolates in 6 patients. In seven patients (33.3 percent) isolates were exclusively aerobic bacteria and in eight both aerobes and anaerobes were present. The anaerobic isolates were clostridia (six), peptostreptococci (five), bacteroides (five), peptococci (three), and one of each of Veillonella, Propionibacterium, Eubacterium, Fusobacterium and Actinomyces. Staphylococcus aureus, generally thought to be the most common cause of subcutaneous infections in addicts, was found only in four (19 percent) patients. The other aerobic isolates were Klebsiella (five) and Enterobacter (four) species. When clinical features or the Gram stain of pus suggest that anaerobic bacteria may be present, antibiotic therapy should be directed against both aerobic and anaerobic bacteria until culture results are available.
D Webb; H Thadepalli
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Western journal of medicine     Volume:  130     ISSN:  0093-0415     ISO Abbreviation:  West. J. Med.     Publication Date:  1979 Mar 
Date Detail:
Created Date:  1979-05-24     Completed Date:  1979-05-24     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410504     Medline TA:  West J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  200-4     Citation Subset:  IM    
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MeSH Terms
Abscess / etiology
Bacterial Infections / etiology*
Cellulitis / etiology
Heroin Dependence / complications
Injections, Intravenous / adverse effects
Myositis / etiology
Skin Diseases, Infectious / etiology*,  microbiology
Staphylococcus aureus / isolation & purification
Substance-Related Disorders / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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