| Skin and muscle involvement as presenting symptoms in four children with familial Mediterranean fever. | |
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MedLine Citation:
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PMID: 19240979 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent attacks of fever and polyserositis. It is the most frequent periodic fever syndrome. In FMF, sterile peritonitis, pleuritis and arthritis are frequently seen in addition to recurrent febrile attacks. Skin and muscle involvement is less common. Here, we report four patients presented with skin lesions or myalgia. Most striking findings in those patients are the absence of other major criteria for FMF and dominancy of skin lesions or myalgia. All four patients had MEFV gene mutations on both alleles. In patients with erysipelas-like lesions or erythema nodosum along with arthritis/arthralgia or recurrent myalgia, FMF should be kept in mind. |
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Authors:
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Salih Kavukcu; Mehmet Türkmen; Alper Soylu; Belde Kasap; Burçak Tatli Güneş |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-02-25 |
Journal Detail:
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Title: Clinical rheumatology Volume: 28 ISSN: 1434-9949 ISO Abbreviation: Clin. Rheumatol. Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-05-27 Completed Date: 2009-08-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8211469 Medline TA: Clin Rheumatol Country: Germany |
Other Details:
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Languages: eng Pagination: 857-60 Citation Subset: IM |
Affiliation:
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Departments of Pediatrics, School of Medicine, Dokuz Eylül University, Mithatpaşa Cad. 665/4, Küçükyali, 35280, Izmir, Turkey. s.kavukcu@deu.edu.tr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Child Colchicine / therapeutic use Erythema Nodosum / diagnosis, etiology, physiopathology Familial Mediterranean Fever / complications, diagnosis*, drug therapy Female Humans Male Muscle, Skeletal / pathology* Muscular Diseases / diagnosis*, drug therapy, etiology Remission Induction Skin / pathology* Skin Diseases / diagnosis*, drug therapy, etiology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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64-86-8/Colchicine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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