| Skin manifestations of mustard gas. A clinical study of 535 patients exposed to mustard gas. | |
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MedLine Citation:
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PMID: 1599263 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: During the Iraq-Iran war (1980-1988), 535 patients who were exposed to mustard gas (one of the chemical warfare agents used by Iraq) were referred to our dermatology department. In this article, we have tried to review the skin manifestations of these patients. OBSERVATIONS: The skin lesions were of early or late onset. The early onset lesions consisted of erythema (76%), bulla (55%), and purpura (1.1%). These lesions were mostly found on the face and skin folds. The late-onset manifestations were pigmentation (20.4%) and desquamation (11.2%). Other complications were ophthalmic (85%), pulmonary (15%), and gastrointestinal (10%). Lymphopenia (7%) was the most serious laboratory disorder reported. Biopsy specimens of the lesions showed subepidermal bullae with mild dermal and epidermal necrosis. CONCLUSIONS: All patients were treated as for burns using sulfadiazine and furacine. All patients were cured in a period of 15 to 45 days. During a 6-month follow-up, no mortality was observed. |
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Authors:
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A Z Momeni; S Enshaeih; M Meghdadi; M Amindjavaheri |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of dermatology Volume: 128 ISSN: 0003-987X ISO Abbreviation: Arch Dermatol Publication Date: 1992 Jun |
Date Detail:
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Created Date: 1992-07-06 Completed Date: 1992-07-06 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 0372433 Medline TA: Arch Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 775-80 Citation Subset: AIM; IM |
Affiliation:
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Department of Dermatology, Isfahan University of Medical Sciences. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anemia / chemically induced Blister / chemically induced Child Combined Modality Therapy Conjunctivitis / chemically induced, therapy Erythema / chemically induced, therapy Female Humans Infant Iran Male Mustard Gas / adverse effects* Pigmentation Disorders / chemically induced, therapy Skin Diseases / chemically induced*, pathology, therapy Skin Diseases, Vesiculobullous / chemically induced, therapy Thrombocytopenia / chemically induced Time Factors Urticaria / chemically induced, therapy |
| Chemical | |
Reg. No./Substance:
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505-60-2/Mustard Gas |
| Comments/Corrections | |
Comment In:
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Arch Dermatol. 1993 Feb;129(2):245
[PMID:
8434986
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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