Document Detail

Skin absorption and protective gloves in dynamite work.
MedLine Citation:
PMID:  7415963     Owner:  NLM     Status:  MEDLINE    
Serious health hazards have been reported from dynamite manufacturing during the last hundred years but many problems are still unsolved concerning biological monitoring and protective clothing. In this study, experiments are reported where ethylene glycol dinitrate (EGDN) has been measured in blood from subjects whose hands were exposed to dynamite vapors only or to the combination of vapors and the solid phase, with an without gloves. Strong indications were found that skin absorption is a major route of entry for EGDN into the body. Rubber gloves were found to absorb considerable amounts of EGDN and also to let it pass thorugh to the skin and the blood. However, rubber gloves with inner cotton gloves seem to constitute some protection if they are changed as frequently as once or twice an hour compared with only using cotton gloves or working bare-handed. Blood samples from cubital veins primarily were found to reflect the local skin absorption of EGDN and not the total uptake. Exhaled air was analyzed at moments of high skin exposure but no EGDN could be detected. Further studies of biological monitoring and protective materials are suggested.
C Hogstedt; R Ståhl
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American Industrial Hygiene Association journal     Volume:  41     ISSN:  0002-8894     ISO Abbreviation:  Am Ind Hyg Assoc J     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-11-20     Completed Date:  1980-11-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0371160     Medline TA:  Am Ind Hyg Assoc J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  367-72     Citation Subset:  IM    
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MeSH Terms
Air Pollutants*
Air Pollutants, Occupational*
Breath Tests
Ethylene Glycols / blood*
Occupational Medicine
Protective Clothing
Protective Devices*
Skin Absorption*
Reg. No./Substance:
0/Air Pollutants; 0/Air Pollutants, Occupational; 0/Ethylene Glycols; 628-96-6/ethylene glycol dinitrate; 9006-04-6/Rubber

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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