Document Detail


SKEWNESS OF TCR Vβ OF PERIPHERAL BLOOD AND SYNOVIAL FLUID OF PATIENTS WITH RHEUMATOID ARTHRITIS.
MedLine Citation:
PMID:  24295183     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
To date, the complete mechanism of rheumatoid arthritis (RA) remain unclear, T cells have been proposed to play an important role in the disease initiation and progression. Presently, some researchers have reported that there were skewed TCR Vβ in different samples of experimental animals or RA patients, such as in the peripheral blood, joints or synovial fluid, however, most of the results were not coincident or even conflict with each other. In this article, with real-time fluorescence quantitative PCR with DNA melting curving technique, we detected the bias of TCR Vβ of RA patients, and found that although most of TCR Vβ usage were different between peripheral blood and synovial fluid, the overview of all the Vβ skewness was similar between the two samples.
Authors:
Jianwei Zhou; Cui Kong; Jiang Yu; Haixin Dong; Chengqiang Jin; Qin Song
Related Documents :
15291873 - Ballooning of the foreskin and physiological phimosis: is there any objective evidence ...
2912223 - Morphological dynamics of ureteral transport. ii. peristaltic patterns in relation to f...
8263963 - Effect of isoproterenol on coronary blood flow and signal transduction responses in thy...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of immunoassay & immunochemistry     Volume:  35     ISSN:  1532-4230     ISO Abbreviation:  J Immunoassay Immunochem     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2013-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963688     Medline TA:  J Immunoassay Immunochem     Country:  England    
Other Details:
Languages:  eng     Pagination:  207-19     Citation Subset:  IM    
Affiliation:
a Clinic Laboratory, Affiliated Hospital of Jining Medical College , Jining , Shandong Province , China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A SIMPLE AND HIGHLY SENSITIVE ELISA FOR SCREENING OF THE ?-THALASSEMIA-1 SOUTHEAST ASIAN-TYPE DELETI...
Next Document:  Nursing genomics: practice implications every nurse should know.