| Skeletal myogenesis: genetics and embryology to the fore. | |
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MedLine Citation:
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PMID: 8389217 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The MyoD family of transcription factors are expressed in the skeletal muscles of vertebrate and invertebrate embryos and have dominant regulatory activities that indicate their important developmental functions in myogenic lineage determination and muscle differentiation. Genetic studies, however, reveal that individually, myoD-related genes are not essential for myogenic lineage determination in mouse and Caenorhabditis elegans embryos, but have differentiation functions and perhaps redundant functions in lineage determination that remain to be defined by further genetic studies. |
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Authors:
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C P Emerson |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Current opinion in genetics & development Volume: 3 ISSN: 0959-437X ISO Abbreviation: Curr. Opin. Genet. Dev. Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1993-07-07 Completed Date: 1993-07-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9111375 Medline TA: Curr Opin Genet Dev Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 265-74 Citation Subset: IM |
Affiliation:
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Institute for Cancer Research, Fox Chase Cancer Center, PA 19111. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acid Sequence Animals Cell Differentiation DNA-Binding Proteins* Embryonic and Fetal Development / genetics Humans Invertebrates / embryology, genetics Molecular Sequence Data Morphogenesis / genetics Multigene Family* Muscle Proteins / genetics*, physiology Muscles / embryology* MyoD Protein Myogenic Regulatory Factor 5 Myogenic Regulatory Factors* Myogenin Nuclear Proteins / genetics*, physiology Phosphoproteins / genetics*, physiology Trans-Activators* Transcription Factors / genetics*, physiology Vertebrates / embryology, genetics |
| Chemical | |
Reg. No./Substance:
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0/DNA-Binding Proteins; 0/MYF5 protein, human; 0/MYOG protein, human; 0/Muscle Proteins; 0/MyoD Protein; 0/MyoD1 myogenic differentiation protein; 0/Myogenic Regulatory Factor 5; 0/Myogenic Regulatory Factors; 0/Myogenin; 0/Nuclear Proteins; 0/Phosphoproteins; 0/Trans-Activators; 0/Transcription Factors; 0/myogenic factor 6 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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