Document Detail


Skeletal muscle oxygen pressure fields in artificially ventilated, critically ill patients.
MedLine Citation:
PMID:  7468124     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The MDO (Mehrdraht Dortmund oberfläche) oxygen electrode was used in a study of skeletal muscle oxygen pressure fields, presented as histograms, in critically ill patients artificially ventilated with gas mixtures of different oxygen concentrations. The histograms were compared with forearm blood flow measurements performed with strain gauge plethysmography. Local blood flow and permeability-surface area product (PS) were also studied by the simultaneous clearances of 133xenon and 51Cr-EDTA. The histogram distribution type was normal, i.e. approximately Gaussian, at arterial oxygen pressure levels between 10 and 18 kPa. At arterial oxygen pressures outside this range the histogram distribution types were abnormal, i.e. they showed a non-symmetrical distribution of oxygen pressure values, but their mean was approximately the same as in the normal histogram. However, there were significantly higher tissue oxygen pressure mean values in the patients (3.43 kPa) than in a group of healthy human volunteers (2.25 kPa). Mean forearm blood flow and the clearances of 133xenon and 51Cr-EDTA showed marked variations during the measurements both intraindividually and interindividually. Mean forearm blood flow and mean clearances of 133xenon showed opposite trends compared with arterial oxygen pressures. Mean clearances of 51Cr--EDTA and means PS showed only minor variations at the different arterial oxygen pressure levels.
Authors:
N Lund; L Jorfeldt; D H Lewis; S Odman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  24     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-04-13     Completed Date:  1981-04-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  347-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Gas Analysis
Chromium Radioisotopes / diagnostic use
Critical Care
Female
Forearm / blood supply
Humans
Male
Middle Aged
Muscles / metabolism*
Oxygen Consumption*
Regional Blood Flow
Respiration, Artificial*
Xenon Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Chromium Radioisotopes; 0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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