Document Detail


Skeletal muscle fibre growth and growth associated myopathy in the domestic chicken (Gallus domesticus).
MedLine Citation:
PMID:  16787849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Genetic selection of broilers may have pushed muscle fibres to their maximum functional size constraints. Broiler (B), female great-grandparent (GGP) and layer (L) lines were weighed, blood sampled and killed from 5 to 25 weeks of age. 2. At 25 weeks, Pectoralis major (Pm) fibre size reached by the B (65.9 microm) and GGP (59.8 microm) were 1.5 times greater than the L (38.1 microm). In the B and GGP lines, fibre growth of the Pm markedly exceeded that of the Biceps femoris (Bf) muscle. However, in the L line, fibre growth of the Pm and Bf muscle was comparable. Connective tissue content was generally higher in the Bf than in the Pm of all lines. 3. Centralised nuclei were observed predominantly in Pm, and may regulate fibre size. Both large muscle fibres and inadequate capillary supply may induce metabolic stress in B and GGP lines due to the large diffusion distances for oxygen, metabolites and waste products. 4. Enzyme markers of muscle damage (creatine kinase (CK), lactate dehydrogenase (LDH) and aspartate aminotransaminase (AST)) and histopathological analysis of Pm and Bf indicated greater myopathy in B and GGP vs L. 5. Regenerative processes were associated with oestrogen secretion. Reduced CK and LDH preceded egg yolk precursor production and increased calcium uptake for eggshell synthesis in all three lines. Oestrogen may stimulate muscle fibre regeneration and recovery as a myo-protective adaptation to potentially detrimental changes in calcium economy during egg production.
Authors:
V E MacRae; M Mahon; S Gilpin; D A Sandercock; M A Mitchell
Related Documents :
2748799 - Adult rat lumbrical muscle fibres are not polyneuronally innervated.
3310519 - The central consequences of the application of capsaicin to one peripheral nerve in adu...
3580829 - A morphometric study on sural nerves in metachromatic leucodystrophy.
2984609 - Tonic depolarization of excitatory nerve terminals in crayfish muscle by high concentra...
1284619 - Study on the formation of neural network in the tongue of gallus domesticus (white legh...
2474009 - Innervation of the guinea pig trachea: a quantitative morphological study of intrinsic ...
12618599 - Muscle-sparing latissimus dorsi myocutaneous flap with maintenance of muscle innervatio...
19891199 - Hip adductor muscle function in forward skating.
6826379 - Fragmentation of inhaled 238puo2 particles in lung.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British poultry science     Volume:  47     ISSN:  0007-1668     ISO Abbreviation:  Br. Poult. Sci.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-21     Completed Date:  2006-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15740290R     Medline TA:  Br Poult Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  264-72     Citation Subset:  IM    
Affiliation:
Roslin Institute (Edinburgh), Roslin, Midlothian, Scotland, UK. vicky.macrae@bbsrc.ac.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Chickens
Creatine Kinase / metabolism
Female
Genetic Predisposition to Disease
Muscle, Skeletal / enzymology,  growth & development*
Muscular Diseases / genetics,  veterinary*
Poultry Diseases / genetics*
Chemical
Reg. No./Substance:
EC 2.7.3.2/Creatine Kinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Leg health and performance of broiler chickens reared in different light environments.
Next Document:  Genetic relationships between feed conversion ratio, growth curve and body composition in slow-growi...