Document Detail


Skeletal muscle fat infiltration: impact of age, inactivity, and exercise.
MedLine Citation:
PMID:  20424803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fat infiltration within the fascial envelope of the thigh or intermuscular adispose tissue (IMAT), has been shown to be associated with both adverse metabolic and mobility impairments in older individuals. More recent findings suggest these fat deposits may be associated with increasing age and inactivity; and perhaps exercise may be able to counter or mitigate this increase in IMAT. This brief report summarizes the literature with respect to IMAT and its relationship to increasing age, physical activity levels, muscle strength, mobility and metabolism in the elderly. Further, we present preliminary data suggesting that IMAT is associated with increasing age in individuals across disease states (r=0.47, p < 0.05), and that resistance exercise can decrease IMAT in older individuals with a variety of co-morbid conditions.
Authors:
R L Marcus; O Addison; J P Kidde; L E Dibble; P C Lastayo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of nutrition, health & aging     Volume:  14     ISSN:  1760-4788     ISO Abbreviation:  J Nutr Health Aging     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-28     Completed Date:  2010-06-16     Revised Date:  2010-10-12    
Medline Journal Info:
Nlm Unique ID:  100893366     Medline TA:  J Nutr Health Aging     Country:  France    
Other Details:
Languages:  eng     Pagination:  362-6     Citation Subset:  IM    
Affiliation:
Department of Physical Therapy, University of Utah, Salt Lake City, UT, USA.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / anatomy & histology*,  metabolism
Adolescent
Adult
Aged
Aged, 80 and over
Aging / physiology*
Body Composition / physiology
Exercise / physiology*
Female
Humans
Male
Middle Aged
Muscle, Skeletal / anatomy & histology*,  metabolism
Resistance Training*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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