Document Detail

Skeletal muscle and bone: effect of sex steroids and aging.
MedLine Citation:
PMID:  18539850     Owner:  NLM     Status:  MEDLINE    
Both estrogen and testosterone are present in males and females. Both hormones contribute to the well being of skeletal muscle and bone in men and women, and there is evidence that the loss of sex hormones is associated with the age-related decline in bone and skeletal muscle mass. Hormonal supplementation of older adults to restore estrogen and testosterone levels to those of young men and women is not without penalty.
Marybeth Brown
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Advances in physiology education     Volume:  32     ISSN:  1522-1229     ISO Abbreviation:  Adv Physiol Educ     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-09     Completed Date:  2008-08-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100913944     Medline TA:  Adv Physiol Educ     Country:  United States    
Other Details:
Languages:  eng     Pagination:  120-6     Citation Subset:  IM    
Center for Gender Physiology, Physical Therapy Program, Biomedical Sciences, University of Missouri, Columbia, Missouri 65211, USA.
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MeSH Terms
Aging / physiology*
Bone Development / physiology*
Bone and Bones / physiology*
Estrogens / physiology
Gonadal Steroid Hormones / physiology*
Muscle, Skeletal / anatomy & histology,  growth & development,  physiology*
Tensile Strength / physiology
Testosterone / physiology
Grant Support
Reg. No./Substance:
0/Estrogens; 0/Gonadal Steroid Hormones; 58-22-0/Testosterone

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