Document Detail


Skeletal changes associated with copper deficiency.
MedLine Citation:
PMID:  6809388     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Copper deficiency has been described in premature infants on hyperalimentation. The bony abnormalities are generalized and are usually associated with anemia and neutropenia. These changes present with normal serum levels of iron, ascorbic acid, calcium, phosphorus, and magnesium, as well as with depressed levels of copper and ceruloplasmin. They appear at about three to nine months of age in infants with a low birth weight who are receiving total parenteral nutrition, but can be prevented by greater than normal maintenance levels of copper supplements. Established bone changes improve rapidly after the administration of therapeutic supplements.
Authors:
T M Allen; A Manoli; R L LaMont
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  -     ISSN:  0009-921X     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  1982 Aug 
Date Detail:
Created Date:  1982-10-12     Completed Date:  1982-10-12     Revised Date:  2005-03-03    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  206-10     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Copper / deficiency*
Humans
Infant
Infant, Newborn
Infant, Premature, Diseases / therapy
Male
Osteoporosis / etiology*,  radiography
Parenteral Nutrition, Total / adverse effects
Chemical
Reg. No./Substance:
7440-50-8/Copper

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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