| Sjögren's Syndrome Associated with Vitamin B(12) Deficiency. | |
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MedLine Citation:
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PMID: 20144108 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Three patients showing Sjögren's syndrome in association with macrocytic anemia due to vitamin B(12) deficiency are described. Antibodies to parietal cells, intrinsic factor and salivary protein were investigated; positive test results were obtained in different combinations. Addisonian pernicious anemia as well as vitamin B(12)-malabsorption because of anti-intrinsic factor antibodies in gastric juice and/or malabsorption due to changes in the intestinal wall induced by Sjögren's syndrome are possible etiological factors. A case of Sjögren's syndrome associated with positive anti-parietal cell antibodies and histaminerefractory achylia is also reported. The concurrence of these two diseases known to be associated with autoimmune responses suggests the possibility of similar pathogenesis. |
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Authors:
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O Wegelius; F Fyhrquist; P L Adner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Scandinavian journal of rheumatology Volume: 16 ISSN: 0300-9742 ISO Abbreviation: Scand. J. Rheumatol. Publication Date: 1987 |
Date Detail:
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Created Date: 2010-02-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0321213 Medline TA: Scand J Rheumatol Country: England |
Other Details:
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Languages: eng Pagination: 184-90 Citation Subset: - |
Affiliation:
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Fourth Department of Medicine, University Central Hospital, Helsinki, Finland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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