Document Detail

Sixty-four-row multisection CT angiography for detection and evaluation of ruptured intracranial aneurysms: interobserver and intertechnique reproducibility.
MedLine Citation:
PMID:  17898200     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: The purpose of this work was to assess intertechnique and interobserver reproducibility of 64-row multisection CT angiography (CTA) used to detect and evaluate intracranial aneurysms. MATERIALS AND METHODS: From October 2005 to November 2006, 54 consecutive patients with nontraumatic subarachnoid hemorrhage (SAH) underwent both CTA and digital substraction angiography (DSA). Four radiologists independently reviewed CT images, and 2 other radiologists reviewed DSA images. Aneurysm diameter (D), neck width (N), and the presence of a branch arising from the sac were assessed. RESULTS: DSA revealed 67 aneurysms in 48 patients and no aneurysm in 6 patients. Mean sensitivity and specificity of CTA for the detection of intracranial aneurysms were, respectively, 94% and 90.2%. For aneurysms less than 3 mm, CTA had a mean sensitivity of 70.4%. Intertechnique and interobserver agreements were good for the detection of aneurysms (mean kappa = 0.673 and 0.732, respectively) and for the measurement of their necks (mean kappa = 0.753 and 0.779, respectively). Intertechnique and interobserver agreements were excellent for the measurement of aneurysm diameters (mean kappa = 0.847 and 0.876, respectively). In addition, CTA was accurate in determining the N/D ratio of aneurysms and adjacent arterial branches. However, the N/D ratio was overestimated by all of the readers at CTA. CONCLUSION: Sixty-four-row multisection CTA is an imaging method with a good interobserver reproducibility and a high sensitivity and specificity for the detection and the morphologic evaluation of ruptured intracranial aneurysms. It may be used as an alternative to DSA as a first-intention imaging technique in patients with SAH.
B Lubicz; M Levivier; O François; P Thoma; N Sadeghi; L Collignon; D Balériaux
Publication Detail:
Type:  Journal Article     Date:  2007-09-26
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  28     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:    2007 Nov-Dec
Date Detail:
Created Date:  2007-11-13     Completed Date:  2008-02-05     Revised Date:  2008-07-10    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1949-55     Citation Subset:  IM    
Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium.
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MeSH Terms
Aged, 80 and over
Aneurysm, Ruptured / radiography*
Angiography, Digital Subtraction
Cerebral Angiography*
Intracranial Aneurysm / radiography*
Middle Aged
Observer Variation
Predictive Value of Tests
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed*
Comment In:
AJNR Am J Neuroradiol. 2008 Jun;29(6):e41-2; author reply e46-7   [PMID:  18372411 ]

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