Document Detail

Sixteen-row multislice computerized tomography angiography in the postoperative evaluation of patients with intracranial aneurysms.
MedLine Citation:
PMID:  17952720     Owner:  NLM     Status:  MEDLINE    
The goal of this study was to assess the diagnostic accuracy of 16-row multislice computed tomography angiography (CTA) compared with digital subtraction angiography (DSA) in the detection of aneurysm remnants and arterial patency after clipping of intracranial aneurysms. Thirty-seven consecutive patients with 40 clipped aneurysms (39 of which had ruptured) were studied with the aid of postoperative CTA and DSA. CTA was performed with a 16-row multislice CT scanner by using collimation of 0.75 mm. Two neuroradiologists evaluated the image quality of CTA and the presence of the residual aneurysms with a 5-point rating scale. DSA was considered a reference standard. Two aneurysms with incomplete closure were identified by the 16-slice CTA reconstructions. With 16-slice CTA, there were no false-positive results of an aneurysm with incomplete closure in any patient. Arterial patency could be reliably evaluated close to the clip. The sensitivity, specificity, and accuracy of 16-slice CTA for aneurysm occlusion and arterial patency were 100%[97.5% confidence interval (CI): 15.8 - 100%], 100% (97.5% CI: 90.7 - 100%) and 100% (97.5% CI: 91.2 - 100%), respectively. The positive and negative predictive values were 100 and 100%, respectively. The mean duration of the examination was 12 min for CTA and 40 min for DSA (p < 0.05). Sixteen-slice CTA was highly cost effective (p < 0.05). Sixteen-slice CTA is a valuable non-invasive diagnostic modality for the assessment of aneurysm remnants and arterial patency in patients after aneurysm clipping. Its high sensitivity and low cost warrant its use for postoperative routine control examinations following clip placement on an aneurysm.
W Chen; Y Yang; J Qiu; Y Peng; W Xing
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  British journal of neurosurgery     Volume:  22     ISSN:  0268-8697     ISO Abbreviation:  Br J Neurosurg     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-04-03     Completed Date:  2008-07-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8800054     Medline TA:  Br J Neurosurg     Country:  England    
Other Details:
Languages:  eng     Pagination:  63-70     Citation Subset:  IM    
Department of Radiology, Third Affiliated Hospital of Suzhou University, Changzhou, Peoples Republic of China.
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MeSH Terms
Angiography, Digital Subtraction / economics,  methods*
Cerebral Arteries / radiography*
Intracranial Aneurysm / radiography*
Middle Aged
Postoperative Period
Predictive Value of Tests
Sensitivity and Specificity
Surgical Instruments
Tomography, X-Ray Computed / economics,  methods*
Treatment Outcome

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