| Sixteen-row multislice computed tomography angiography in the diagnosis and characterization of intracranial aneurysms: comparison with conventional angiography and intraoperative findings. | |
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MedLine Citation:
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PMID: 18518726 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECT: The goal of this study was to prospectively compare the effectiveness of 16-slice computed tomography (CT) angiography with that of conventional digital subtraction (DS) angiography and the surgical findings used to detect and characterize intracranial aneurysms. METHODS: Two hundred forty-four consecutive patients underwent both CT angiography and DS angiography no more than 3 days apart. Computed tomography angiography was performed with a 16-row multislice CT scanner in which a collimation of 0.75 mm was used. Two observers independently reviewed the CT images, and 1 of the 3 attending neuroradiologists reviewed the DS angiograms. They determined the presence, location, quantitation, and characterization of the intracranial aneurysms. Statistical results were calculated independently for the image interpretation performed by the 2 CT scan readers and the DS angiogram reader by using the combination of DS angiography or intraoperative findings or both as a reference standard. RESULTS: One hundred thirty-six patients harboring 153 intracranial aneurysms were included in this series. There was no statistically significant difference in sensitivity between 16-slice CT angiography and conventional DS angiography (p > 0.05). The sensitivities of 16-slice CT angiography for aneurysms < 5 mm, 5-10 mm, and > 10 mm were 94.8, 100, and 100%, respectively, on a per-aneurysm basis. The overall sensitivity and specificity of CT angiography for aneurysms were 98.0 and 99.1%, respectively. Sixteen-slice CT angiograms were clearer and more accurate in depicting the relationship of aneurysms to bone structures and adjacent branch vessels. CONCLUSIONS: Computed tomography angiography using a 16-slice scanner is an accurate tool for detecting and characterizing intracranial aneurysms, including small aneurysms. Noninvasive 16-slice CT angiography will become a viable replacement for conventional DS angiography in the diagnosis and characterization of aneurysms. |
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Authors:
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Wenhua Chen; Yilin Yang; Wei Xing; Jianguo Qiu; Ya Peng |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of neurosurgery Volume: 108 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 2008 Jun |
Date Detail:
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Created Date: 2008-06-03 Completed Date: 2008-07-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: United States |
Other Details:
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Languages: eng Pagination: 1184-91 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology and Neurosurgery, The Third Affiliated Hospital of Suzhou University, Changzhou, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Angiography, Digital Subtraction Cerebral Angiography / methods* Child Female Humans Imaging, Three-Dimensional* Intracranial Aneurysm / radiography*, surgery Male Middle Aged Predictive Value of Tests Prospective Studies Reproducibility of Results Time Factors Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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