Document Detail

Sixteen-channel multidetector row computed tomography versus coronary angiography in a surgical view.
MedLine Citation:
PMID:  16467064     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Invasive coronary angiography (ICA) is the gold standard for the diagnosis of coronary artery disease and also for imaging procedures for preoperative planning of coronary artery bypass grafting (CABG). Sixteen-multidetector row computed tomography (MDCT) represents an alternative depiction of coronary vessels. METHODS: Preoperative exams included ICA and MDCT in 50 patients. Two blinded surgical readers independently investigated both diagnostic modalities regarding location, severity, and morphology of the stenoses. The right coronary artery, left anterior descending branch, and circumflex branch--each divided in 3 sections--and the left main artery with a diameter (3) 1.5 mm were rated in both procedures, and the percentage of complete evaluations by MDCT was assessed. RESULTS: Heart rate was 72 +/- 8 bpm. Forty-six percent of patients received a complete MDCT evaluation, and 54% received an incomplete MDCT evaluation. In 62% of these incompletely examined patients, 1 branch was not completely analyzable, in 31% 2 branches; and in 7% all 3 branches. In total, 9% of all segments were incompletely assessed. Investigators detected coronary stenoses in complete evaluations with a sensitivity of 94% and a specificity of 95%. Positive predictive value was 87% and negative predictive value was 98%. Plaque classification in soft and hard plaques was possible. CONCLUSION: Sixteen-MDCT is not a viable alternative diagnostic tool at present. However, although the percentage of incomplete evaluated patients is more then 50%, only 9% of all segments were incompletely assessable. If this technology can be further improved, especially its software, it will become a valid diagnostic tool for coronary artery disease.
André Plass; Bernhard Baumert; Achim Häussler; Jürg Grünenfelder; Simon Wildermuth; Franz R Eberli; Gregor Zund; Michele Genoni
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The heart surgery forum     Volume:  9     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2006  
Date Detail:
Created Date:  2006-02-09     Completed Date:  2006-12-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E572-8     Citation Subset:  IM    
Clinic for Cardiovascular Surgery, University Hospital Zurich, Switzerland.
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MeSH Terms
Coronary Angiography / methods*
Coronary Artery Disease / radiography*,  surgery*
Middle Aged
Preoperative Care / methods*
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray Computed / instrumentation,  methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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