Document Detail

Six-minute walk distance and work relationship with incremental treadmill cardiopulmonary exercise test in COPD.
MedLine Citation:
PMID:  22524795     Owner:  NLM     Status:  Publisher    
Introduction:  Cardiopulmonary exercise testing (CPET) is increasingly used to evaluate the overall impact of the illness on patients with COPD.While laboratory tests of exercise performance are costly, the six-minute walk test (6-MWT) can be more easily performed. Although the main outcome commonly used in this field test is the distance walked in 6 minutes (6-MWD), this measure does not account for differences in body weight. Previous studies showed a good correlation between the work performed during the 6-MWT with incremental cycling CPET, an exercise modality more associated with quadriceps fatigability and lower peak oxygen consumption () than incremental walking tests. Objective:  Evaluate the correlation between the 6-MWD and its derivative body weight-walking distance product, an estimation of the work performed during the 6-MWT, with peak from a treadmill CPET. Methods:  Thirty COPD patients (FEV(1) = 39 ± 13%; peak = 68.7 ± 17.4% predicted) performed CPET to the limit of tolerance on a treadmill and 6-MWT, 48 h apart.6-MWD and work were correlated to resting and exercise functional variables. Results:  The work of walking during the 6-MWT provided greater associations with peak than observed with 6-MWD. This was the case for FEV(1) , FVC, IC, D(L) CO, peak , , , and double product (r=0.57, r=0.57, r=0.73, r=0.7, r=0.75, r=0.65, r=0.51, and r= 0.4, respectively; all p<0.05). Conclusion:  A better association was found between the work estimated from the 6-MWT and peak achieved during CPET, in this case with a treadmill, than the 6-MWD alone. © 2012 Blackwell Publishing Ltd.
Karla Poersch; Danilo C Berton; Daversom Bordin Canterle; Juliano Castilho; André L Lopes; Jocelito Martins; Alvaro R Oliveira; Paulo José Zimermann Teixeira
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-24
Journal Detail:
Title:  The clinical respiratory journal     Volume:  -     ISSN:  1752-699X     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101315570     Medline TA:  Clin Respir J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Blackwell Publishing Ltd.
Universidade Federal do Rio Grande do Sul (UFRGS); Instituto de Ciências da Saúde, Universidade Feevale; Universidade Federal de Ciências da Saúde dePorto Alegre, Pavilhão Pereira Filho, Santa Casa de Porto Alegre, Porto Alegre, Brazil.
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