Document Detail

Six chromophobe cell carcinomas and one mixed renal cell carcinoma with chromophobe cell features: clinical and pathological implications.
MedLine Citation:
PMID:  8813909     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the incidence and clinical and pathological features of chromophobe cell carcinoma (CCC) among renal cell carcinomas (RCCs). MATERIALS AND METHODS: The records and nephrectomy samples from 166 patients who were operated on and followed up thereafter with a diagnosis of RCC were re-evaluated. New sections were cut and specific staining performed when deemed necessary. RESULTS: Of 166 patients with RCC, six were diagnosed as having CCC and, unusually, one patient had a mixed RCC with areas of CCC. Neither the symptoms nor radiological features of these seven patients differed from those of the patients with RCC; the serum ferritin levels of these seven patients were also within the normal range. These patients appeared to have a favourable clinical course. CONCLUSION: Chromophobe cell carcinoma is a distinct entity and must be distinguished particularly from oncocytoma and other variants of RCC. Although it seems to have a low malignant potential, metastatic CCC may have a worse prognosis.
A Usubütün; M C Uygur; A Ayhan; H Ozen; D Remzi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of urology     Volume:  78     ISSN:  0007-1331     ISO Abbreviation:  Br J Urol     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-10-24     Completed Date:  1996-10-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15740090R     Medline TA:  Br J Urol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  183-6     Citation Subset:  IM    
Department of Urology, School of Medicine, Hacettepe University, Ankara, Turkey.
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MeSH Terms
Adenocarcinoma / pathology*,  surgery
Carcinoma, Renal Cell / pathology*,  surgery
Disease-Free Survival
Kidney Neoplasms / pathology*,  surgery
Middle Aged
Neoplasm Staging
Organ Size
Treatment Outcome

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