| Site-specific functionalization of RNA molecules by an unnatural base pair transcription system via click chemistry. | |
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MedLine Citation:
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PMID: 23032097 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Toward new biotechnology by genetic alphabet expansion, we developed an efficient site-specific labeling method for large RNA molecules. The combination of unnatural base pair transcription and post-transcriptional modification by click chemistry enables simple RNA labeling with a wide variety of functional groups at desired positions, in a one-pot reaction. |
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Authors:
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Takumi Ishizuka; Michiko Kimoto; Akira Sato; Ichiro Hirao |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-3 |
Journal Detail:
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Title: Chemical communications (Cambridge, England) Volume: - ISSN: 1364-548X ISO Abbreviation: Chem. Commun. (Camb.) Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610838 Medline TA: Chem Commun (Camb) Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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RIKEN Systems and Structural Biology Center (SSBC), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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