| Site predilection of airway inflammation by emphysema type. | |
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MedLine Citation:
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PMID: 6547594 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To elucidate interrelations of airway inflammation and emphysema, bronchi from subjects with severe panlobular and centrilobular disease and normal lungs were compared. This disclosed an intense infiltration with chronic inflammatory cells, mucous gland hypertrophy, and thickening of bronchi, primarily in association with emphysema having a panlobular configuration. These changes complement a generalized thickening and inflammation of nonrespiratory bronchioles previously observed in these cases. We conclude that the panlobular pattern may be a close function of inflammatory thickening of the conductive airways to respective lungs and lung parts, but centrilobular emphysema is not reliant on these changes. The precursory defect for the centrilobular lesion instead has been shown to be a more peripherally oriented respiratory bronchiolitis around the centers of lobules. |
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Authors:
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A Linhartová; A E Anderson; A G Foraker |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of pathology & laboratory medicine Volume: 108 ISSN: 0003-9985 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 1984 Aug |
Date Detail:
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Created Date: 1984-08-22 Completed Date: 1984-08-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 662-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Animals Bronchi / pathology Bronchitis / pathology* Dogs Emphysema / pathology* Humans Lung / pathology Pulmonary Alveoli / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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