Document Detail

Sister chromatid exchange in lymphocytes of patients with cancer of the larynx.
MedLine Citation:
PMID:  1858972     Owner:  NLM     Status:  MEDLINE    
The frequency of sister chromatid exchange (SCE) was studied in cultured peripheral lymphocytes from 15 untreated patients with carcinoma of the larynx and 10 healthy control subjects. Bromodeoxyuridine-incorporated chromosomes were treated with Hoechst 33258 and stained according to conventional methods. To measure SCE frequency, at least 15 mitoses per donor were evaluated. The SCE values were found to be higher in cancer cases than in control cases.
R M Nohutcu; S Emre; M Sakizli; B Gürsel; Y K Eratalay; N Hosal
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of otolaryngology     Volume:  12     ISSN:  0196-0709     ISO Abbreviation:  Am J Otolaryngol     Publication Date:    1991 Mar-Apr
Date Detail:
Created Date:  1991-08-23     Completed Date:  1991-08-23     Revised Date:  2007-07-24    
Medline Journal Info:
Nlm Unique ID:  8000029     Medline TA:  Am J Otolaryngol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  101-3     Citation Subset:  IM    
Department of Periodontology, Hacettepe University Faculty of Dentistry, Ankara, Turkey.
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MeSH Terms
Carcinoma / blood,  genetics*
Laryngeal Neoplasms / blood,  genetics*
Lymphocytes / ultrastructure*
Middle Aged
Sister Chromatid Exchange*
Smoking / blood,  genetics

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