| Sirolimus-eluting and paclitaxel-eluting stents for the treatment of coronary bifurcations. | |
| | |
MedLine Citation:
|
PMID: 18946894 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The aim of the study was to compare the outcomes of sirolimus-eluting (SES) and paclitaxel-eluting (PES) stent implantation in coronary bifurcations treated with either a 1-stent or 2-stent strategy. METHODS: The study used a retrospective cohort analysis of consecutive de novo bifurcations, excluding left main, treated with SES or PES between April 2003 and June 2005. RESULTS: We identified 170 bifurcations in 161 patients treated with SES and 119 bifurcations in 112 patients treated with PES. During a median follow-up of 1,061 days (interquartile range 814-1,314), 43 patients (26.7%) in the SES group and 28 (25.0%) in the PES group had a major adverse cardiac event (P = .78). The angiographic restenosis rate per bifurcation was 20.9% and 25.9%, respectively (P = .41). There was no difference overall in the occurrence of target lesion revascularization (TLR) per bifurcation, 22 with SES (12.9%) and 18 with PES (15.1%), P = .61. The TLR rate was similar for SES and PES in bifurcations treated with 1 stent (6.7% vs 11.4%, P = .40) and in bifurcations treated with both branch stenting (20.0% vs 20.4%, P =1.0). CONCLUSIONS: In this cohort, the long-term clinical outcomes appear similar overall between SES and PES in the treatment of coronary bifurcations irrespective of whether a 1-stent or 2-stent strategy was used. |
| | |
Authors:
|
Azeem Latib; John Cosgrave; Cosmo Godino; Asif Qasim; Simon J Corbett; Davide Tavano; Nuccia Morici; Nicole Cristell; Alaide Chieffo; Mauro Carlino; Matteo Montorfano; Flavio Airoldi; Antonio Colombo |
Related Documents
:
|
14557354 - Sirolimus-eluting stent implantation in st-elevation acute myocardial infarction: a cli... 15939104 - The sv stent study: a prospective, multicentre, angiographic evaluation of the biodivys... 21135814 - Synergistic effect of adipose-derived stem cell therapy and bone marrow progenitor recr... 14587644 - The prognostic value of il-8 for cardiac events and restenosis in patients with coronar... 18497554 - The effect of postural changes (leg lifting) on tissue doppler parameters in coronary a... 17954054 - Sequential hybrid carotid and coronary artery revascularization: immediate and mid-term... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: American heart journal Volume: 156 ISSN: 1097-6744 ISO Abbreviation: Am. Heart J. Publication Date: 2008 Oct |
Date Detail:
|
Created Date: 2008-10-22 Completed Date: 2008-11-14 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370465 Medline TA: Am Heart J Country: United States |
Other Details:
|
Languages: eng Pagination: 745-50 Citation Subset: AIM; IM |
Affiliation:
|
Interventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty, Transluminal, Percutaneous Coronary* Coronary Angiography Coronary Disease / radiography, therapy* Drug-Eluting Stents* Female Humans Immunosuppressive Agents / administration & dosage* Male Middle Aged Paclitaxel / administration & dosage* Retrospective Studies Sirolimus / administration & dosage* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Immunosuppressive Agents; 33069-62-4/Paclitaxel; 53123-88-9/Sirolimus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of disclosing financial interests on participation in medical research: a randomized vignett...
Next Document: Nephrotoxicity of iodixanol versus ioversol in patients with chronic kidney disease: the Visipaque A...