Document Detail

MedLine Citation:
PMID:  12940384     Owner:  NLM     Status:  MEDLINE    
Sirenomelia is a rare congenital anomaly with incidence of 1.5-4.2 per 100,000 births. Vascular steal phenomenon, posterior axial mesodermal defect or teratogenic defects have been implied in its pathogenesis. The authors present two cases with associated upper limb involvement and vertebral defects and complete absence of one lower limb bones in one case. Autopsy revealed abnormalities in internal organs. Both cases were associated with single umbilical artery and severe oligohyramnios. Sirenomelia should be suspected in antenatal period in cases presenting with severe oligohydramnios and intrauterine growth retardation for a early diagnosis and appropriate management of pregnancy.
Antima Banerjee; M M A Faridi; Tushar K Banerjee; R N Mandal; Anju Aggarwal
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  70     ISSN:  0019-5456     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-08-27     Completed Date:  2003-09-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  589-91     Citation Subset:  IM    
Department of Pediatrics, University College of Medical Sciences, New Delhi.
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MeSH Terms
Ectromelia / diagnosis*
Fatal Outcome
Infant, Newborn

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