Document Detail


Sir Howard Walter Florey--the force behind the development of penicillin.
MedLine Citation:
PMID:  15185195     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The development of penicillin was a watershed in the battle against infectious diseases. The primary individuals responsible for its discovery and development were Sir Alexander Fleming, Sir Howard Walter Florey, and Ernst B. Chain, now primary figures in the annals of medical history. The individual who serendipitously "discovered" penicillin was Sir Alexander Fleming. Despite the determination displayed by Fleming, little notice was given to his discovery for more than a decade, and the active substance was not isolated. Finally, in 1939, Florey, along with Chain, led a team of British scientists who successfully manufactured the drug from the liquid broth in which penicillin grows. They, along with Fleming, were given the 1945 Nobel Prize in Physiology or Medicine for their roles in the discovery and development of this agent. This biography focuses on the life and work of Sir Howard Walter Florey.
Authors:
B Lee Ligon
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Publication Detail:
Type:  Biography; Historical Article; Journal Article; Portraits    
Journal Detail:
Title:  Seminars in pediatric infectious diseases     Volume:  15     ISSN:  1045-1870     ISO Abbreviation:  Semin Pediatr Infect Dis     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-06-08     Completed Date:  2005-01-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9008093     Medline TA:  Semin Pediatr Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  109-14     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Baylor College of Medicine, 66212 Fannin, A-150, Houston, TX 77030, USA. bligon@bcm.tmc.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Australia
Bacterial Infections / drug therapy
Clinical Trials as Topic
History, 20th Century
Humans
Nobel Prize
Penicillins / biosynthesis,  history*,  isolation & purification,  therapeutic use
Streptococcal Infections / drug therapy
Streptococcus / drug effects
Chemical
Reg. No./Substance:
0/Penicillins
Personal Name Subject
Personal Name Subject:
Howard Walter Florey

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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