| Sinusoidal obstruction syndrome. | |
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MedLine Citation:
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PMID: 21055688 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Sinusoidal obstruction syndrome (SOS), formerly named venoocclusive disease, is a well-known complication of hematopoietic stem cell transplantation and ingestion of food or drinks contaminated by pyrrolizidine alkaloids. Many other drugs and toxins have been associated with SOS, including several chemotherapeutic agents and immunosuppressors. SOS contributes to significant morbidity and mortality in all these settings. This review describes the histologic lesions of SOS, details its pathogenesis as it is understood today, specifies the recent data on its causes and how it may influence clinical management of colorectal liver metastases, and discusses the current knowledge on diagnosis and preventive options. |
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Authors:
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Laura Rubbia-Brandt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinics in liver disease Volume: 14 ISSN: 1557-8224 ISO Abbreviation: Clin Liver Dis Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9710002 Medline TA: Clin Liver Dis Country: United States |
Other Details:
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Languages: eng Pagination: 651-68 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Clinical Pathology of University Hospital, Geneva, Switzerland. laura.rubbia-brandt@hcuge.ch |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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