| Sinusoidal fetal heart rate pattern associated with alphaprodine administration. | |
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MedLine Citation:
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PMID: 733135 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sinusoidal fetal heart rate patterns were observed in 42.5% of a group of 40 women who had received alphaprodine (Nisentil) for relief of labor pain. Analysis showed that the pattern appeared approximately 19 minutes following alphaprodine administration and persisted for approximately 60 minutes. In a control group of 18 patients who did not receive narcotic analgesia, and intermittent sinusoidal pattern was observed in one patient. All babies with sinusoidal heart rate during labor had 1-minute Apgar scores of 7 or greater except two in the study group. Both these neonates had low Apgar scores directly associated with complications at delivery. All 5-minute Apgar scores were 7 or greater, and there were no perinatal deaths. |
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Authors:
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J H Gray; D W Cudmore; E R Luther; T R Martin; A J Gardner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 52 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1978 Dec |
Date Detail:
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Created Date: 1979-03-24 Completed Date: 1979-03-24 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 678-81 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Alphaprodine
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adverse effects*,
therapeutic use Apgar Score Arrhythmias, Cardiac / chemically induced Female Fetal Heart / drug effects, physiopathology* Heart Rate / drug effects* Humans Infant, Newborn Labor, Obstetric Pain / drug therapy Pregnancy |
| Chemical | |
Reg. No./Substance:
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77-20-3/Alphaprodine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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