Document Detail

Sinusoidal fetal heart rate pattern associated with butorphanol administration.
MedLine Citation:
PMID:  3945449     Owner:  NLM     Status:  MEDLINE    
One hundred nineteen fetal heart rate monitor tracings from term-pregnant patients in labor were reviewed by two independent observers to test the hypothesis that Stadol administration to mothers does not result in sinusoidal fetal heart rate pattern. There was agreement with regard to the interpretation of the tracings in 106 instances. Fifty-one patients received intravenous Stadol for narcotic analgesia. Seventy-five percent of these patients demonstrated a transient sinusoidal fetal heart rate pattern after Stadol administration. In a small number of patients, this pattern recurred either with or without additional Stadol treatment. In contrast, patients who did not receive Stadol therapy (N = 55) demonstrated a significantly lower incidence of sinusoidal fetal heart rate pattern (13%), the duration of which was significantly shorter than that seen in the former group. From these we conclude that Stadol therapy during labor is strongly associated with the appearance of sinusoidal fetal heart rate pattern. There were no short-term maternal or neonatal adverse sequelae. In the absence of other fetal heart rate signs suggestive of fetal distress, the presence of sinusoidal fetal heart rate pattern after Stadol administration does not indicate fetal hypoxia.
C G Hatjis; P J Meis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  67     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-03-26     Completed Date:  1986-03-26     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  377-80     Citation Subset:  AIM; IM    
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MeSH Terms
Anesthesia, Obstetrical
Butorphanol / administration & dosage,  pharmacology*
Diagnosis, Differential
Fetal Heart / drug effects*
Fetal Hypoxia / diagnosis
Fetal Monitoring
Heart Rate / drug effects*
Infant, Newborn
Injections, Intravenous
Morphinans / pharmacology*
Reg. No./Substance:
0/Morphinans; 42408-82-2/Butorphanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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