Document Detail

Sinus rhythm mapping in a canine model of ventricular tachycardia.
MedLine Citation:
PMID:  2456542     Owner:  NLM     Status:  MEDLINE    
The relationship between electrograms recorded during sinus rhythm and the activation sequence during ventricular tachycardia induced by programmed stimulation was investigated in a canine model of myocardial infarction. Thirteen dogs were studied 3 days (n = 10) or 14 days (n = 3) after coronary occlusion. Sixty-three unipolar electrograms were simultaneously recorded with a sock electrode array connected to a digital recording system, and analyzed by computer. Bipolar electrograms were recorded sequentially from the same sites with an analog recorder. Categories of unipolar electrograms were defined with reference to the QRS complex during sinus rhythm as follows: Class A included electrograms with an intrinsic deflection inscribed within the QRS complex, class B included those which did not exhibit any intrinsic rs deflection, and class C included those with an intrinsic deflection inscribed later than QRS. The epicardial distribution of each class of electrograms was significantly different between the preparations with, and those without inducible tachycardia (72% versus 63% of electrograms being in class A, 20% versus 35% in class B, and 8% versus 2% in class C; p less than 0.005). When tachycardia was inducible, class C epicardial electrograms were located in an area extending across the region of infarction, which corresponded to the common reentrant pathway of figure-of-eight patterns mapped during tachycardia. When ventricular tachycardia was not inducible, class B electrograms were recorded all over this region. The morphology of bipolar electrograms had no predictive value in identifying the common reentrant pathway. These results support the view that the inducibility of reentrant tachycardia is dependent upon critically located delayed activity detected during sinus rhythm by unipolar recordings.
P L Pagé; R Cardinal; P Savard; M Shenasa
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  11     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-08-31     Completed Date:  1988-08-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  632-44     Citation Subset:  IM    
Department of Surgery, Pharmacology and Medicine, Sacré-Coeur Hospital, Université de Montréal.
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MeSH Terms
Electric Stimulation / methods
Electrocardiography / methods
Electrophysiology / methods*
Heart Rate*
Heart Ventricles
Myocardial Infarction / physiopathology
Signal Processing, Computer-Assisted
Sinoatrial Node / physiopathology
Tachycardia / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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