| Sinus bradycardia, Wolff Parkinson White, and left ventricular noncompaction: an embryologic connection? | |
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MedLine Citation:
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PMID: 17786379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Left ventricular noncompaction (LVNC) is an uncommon disorder that has recently been recognized as a distinct cardiomyopathy. LVNC is thought to result from an arrest in the normal process of myocardial compaction. The association of Wolff-Parkinson-White with noncompaction of the left ventricle is well recognized. Sinus bradycardia has also been associated with LVNC, although less frequently than that of Wolff-Parkinson-White. We report an infant with LVNC, Wolff-Parkinson-White, and progressive sinus bradycardia who had a myocardial vascular abnormality in the region of the sinus node evident on autopsy. We propose that the progressive nature of the conduction system abnormality was as a result of abnormal angiogenesis. |
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Authors:
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Jack C Salerno; Terrence U Chun; Joe C Rutledge |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-09-01 |
Journal Detail:
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Title: Pediatric cardiology Volume: 29 ISSN: 0172-0643 ISO Abbreviation: Pediatr Cardiol Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-05-12 Completed Date: 2008-11-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 679-82 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Children's Hospital and Regional Medical Center and University of Washington School of Medicine, Seattle, WA 98105, USA. jack.salerno@seattlechildrens.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Autopsy Bradycardia / embryology* Cardiomyopathies / congenital, pathology* Fatal Outcome Heart Ventricles / abnormalities* Humans Infant Male Ventricular Dysfunction, Left / congenital, embryology* Wolff-Parkinson-White Syndrome / embryology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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