| Sinonasal cancer and wood dust exposure: results from a case-control study. | |
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MedLine Citation:
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PMID: 8059769 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case-control study of occupational risk factors for sinonasal cancer was conducted in France in 1986-1988. The study included 207 histologically confirmed cases and 409 controls. Among the male cases were 59 men with squamous cell carcinoma and 82 with adenocarcinoma. The risk of sinonasal cancer in relation to wood dust exposure was studied in these two groups. The analysis was based on a case-by-case assessment of exposure by an industrial hygienist. Hardwood and softwood were distinguished. An approximate twofold increase in risk for squamous cell carcinomas was observed for cases whose first exposure to either hardwood or softwood occurred before 1945; however, the two types of exposure were highly correlated. An exposure to wood dust--from either hardwood alone or hardwood and other kinds of wood--was found for all but two of the 82 male cases with adenocarcinoma. The effects of different elements of exposure to hardwood (duration, level, period) were studied in detail with a logistic model. Two components of exposure--duration and average level--contributed independently to the overall very elevated risk. Additional exposure to wood other than hardwood did not increase the risk. |
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Authors:
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A Leclerc; M Martinez Cortes; M Gérin; D Luce; J Brugère |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of epidemiology Volume: 140 ISSN: 0002-9262 ISO Abbreviation: Am. J. Epidemiol. Publication Date: 1994 Aug |
Date Detail:
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Created Date: 1994-09-15 Completed Date: 1994-09-15 Revised Date: 2006-04-19 |
Medline Journal Info:
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Nlm Unique ID: 7910653 Medline TA: Am J Epidemiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 340-9 Citation Subset: IM |
Affiliation:
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Unité 88, INSERM, Paris, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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epidemiology,
etiology* Aged Carcinoma, Squamous Cell / epidemiology, etiology* Case-Control Studies Dust / adverse effects* Environmental Monitoring France / epidemiology Humans Logistic Models Male Middle Aged Nose Neoplasms / epidemiology, etiology* Occupational Diseases / epidemiology, etiology* Paranasal Sinus Neoplasms / epidemiology, etiology* Risk Factors Wood* |
| Chemical | |
Reg. No./Substance:
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0/Dust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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