Document Detail


Single v. multiple measures of skin carotenoids by resonance Raman spectroscopy as a biomarker of usual carotenoid status.
MedLine Citation:
PMID:  23351238     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Resonance Raman spectroscopy (RRS) is a non-invasive method of assessing carotenoid status in the skin, which has been suggested as an objective indicator of fruit/vegetable intake. The present study assessed agreement and identified predictors of single v. multiple RRS measures of skin carotenoid status. A total of seventy-four participants had their skin carotenoid status measured in the palm of the hand by RRS at six time points over 6 months. Questionnaires were administered to collect information on demographic, lifestyle and dietary data. Mean age of the participants was 36·6 years, 62·2 % were female, 83·8 % Caucasian and 85·1 % were non-smoking at baseline. There was a good agreement between a single measure of skin carotenoids by RRS and multiple measures (weighted κ = 0·80; 95 % CI 0·72, 0·88). The same variables were significantly associated with carotenoid status based on single or multiple measures, including a positive association with intake of total carotenoids (P< 0·01) and an inverse association with season of measurement (P≤ 0·05). The exception was recent sun exposure, which emerged as a significant predictor of lower carotenoid status only when using multiple RRS measures (P≤ 0·01). A single RRS measure was reasonably accurate at classifying usual skin carotenoid status. Researchers using RRS may want to take into account other factors that are associated with the biomarker, including season of measurement and recent sun exposure.
Authors:
Stephanie Scarmo; Brenda Cartmel; Haiqun Lin; David J Leffell; Igor V Ermakov; Werner Gellermann; Paul S Bernstein; Susan T Mayne
Related Documents :
10597988 - Potential gains in life expectancy or years of potential life lost: impact of competing...
20881628 - Mortality surveillance of a us wide cohort of chemical industry workers.
15075158 - Season of birth is not associated with risk of early adult death in rural senegal.
23053858 - Gender differences in contrast-enhanced magnetic resonance imaging after acute myocardi...
23093728 - Three peaks in the polymerase chain reaction fragile x analysis.
9071908 - Diet and prostate cancer: a case-control study.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-28
Journal Detail:
Title:  The British journal of nutrition     Volume:  -     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-7     Citation Subset:  -    
Affiliation:
Department of Chronic Disease Epidemiology, Yale School of Public Health, 60 College Street, PO Box 208034, New Haven, CT 06520-8034, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Role of testosterone in memory impairment of Alzheimer disease induced by Streptozotocin in male rat...
Next Document:  Predictors of Discrepancies in Parkinson's Disease Patient and Caregiver Ratings of Apathy, Disinhib...