| Single-sided continuous optoelectrowetting (SCOEW) for droplet manipulation with light patterns. | |
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MedLine Citation:
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PMID: 20448870 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Electrowetting-on-dielectric (EWOD) promises to be an important lab-on-a-chip approach for effectively manipulating droplets with electric field-controlled surface tension. Droplets manipulated in electrowetting-based devices are typically sandwiched between two parallel plates and actuated by digital electrodes. The size of pixilated electrodes limits the minimum droplet size that can be manipulated. Here, we report on a single-sided continuous optoelectrowetting (SCOEW) mechanism that enables light-patterned electrowetting modulation for continuous droplet manipulation on an open, featureless, and photoconductive surface. SCOEW overcomes the size limitation of physical pixilated electrodes by utilizing dynamic and reconfigurable optical patterns and enables the continuous transport, splitting, merging, and mixing of droplets with volumes ranging from 50 microL to 250 pL, over 5-orders of magnitude. This single-sided open configuration provides a flexible interface for integration with other microfluidic components, such as sample reservoirs through simple tubing. Light-triggered, parallel, and volume-tunable droplet injection with volume variation less than 1% has been demonstrated with SCOEW. The unique lateral field-driven optoelectrowetting mechanism also enables extremely low light intensity actuation, and droplet manipulation can be achieved by directly positioning the SCOEW chip on a LCD screen used in a laptop or portable cellular phone. |
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Authors:
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Sung-Yong Park; Michael A Teitell; Eric P Y Chiou |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-05-06 |
Journal Detail:
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Title: Lab on a chip Volume: 10 ISSN: 1473-0197 ISO Abbreviation: Lab Chip Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-17 Completed Date: 2010-08-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101128948 Medline TA: Lab Chip Country: England |
Other Details:
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Languages: eng Pagination: 1655-61 Citation Subset: IM |
Affiliation:
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Department of Mechanical and Aerospace Engineering, University of California at Los Angeles (UCLA), 43-147 Eng. IV, 420 Westwood Plaza, Los Angeles, CA 90095-1597, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Equipment Design Equipment Failure Analysis Light Microfluidic Analytical Techniques / instrumentation* Micromanipulation / instrumentation* Optical Devices* Solutions / chemistry*, isolation & purification* |
| Grant Support | |
ID/Acronym/Agency:
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PN2EY018228/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Solutions |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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