| Single photon emission computed tomography (SPECT) brain imaging using N,N,N'-trimethyl-N'-(2 hydroxy-3-methyl-5-123I-iodobenzyl)-1,3-propanediamine 2 HCl (HIPDM): intractable complex partial seizures. | |
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MedLine Citation:
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PMID: 3489907 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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HIPDM-SPECT brain imaging was performed in four patients with intractable complex partial seizures (CPS). Three patients had an epileptogenic focus in one temporal lobe and underwent anterior temporal lobectomy. Interictal HIPDM-SPECT demonstrated decreased regional cerebral perfusion (rCP) in the epileptogenic area in only one patient, but ictal studies showed increased rCP in the epileptic foci of all three patients. In the fourth patient, interictal HIPDM-SPECT showed increased rCP in the area of epileptogenic focus; when antiepileptic medication was taken, rCP decreased. HIPDM-SPECT brain imaging is useful for localizing epileptogenic foci in CPS. |
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Authors:
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B I Lee; O N Markand; A R Siddiqui; H M Park; B Mock; H H Wellman; R M Worth; M K Edwards |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurology Volume: 36 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 1986 Nov |
Date Detail:
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Created Date: 1986-11-21 Completed Date: 1986-11-21 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1471-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Brain / radionuclide imaging* Cerebrovascular Circulation Epilepsy, Temporal Lobe / radionuclide imaging* Female Humans Iodobenzenes / diagnostic use* Male Tomography, Emission-Computed* |
| Chemical | |
Reg. No./Substance:
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0/Iodobenzenes; 84718-97-8/N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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