Document Detail

Single photon emission computed tomography (SPECT) brain imaging using N,N,N'-trimethyl-N'-(2 hydroxy-3-methyl-5-123I-iodobenzyl)-1,3-propanediamine 2 HCl (HIPDM): intractable complex partial seizures.
MedLine Citation:
PMID:  3489907     Owner:  NLM     Status:  MEDLINE    
HIPDM-SPECT brain imaging was performed in four patients with intractable complex partial seizures (CPS). Three patients had an epileptogenic focus in one temporal lobe and underwent anterior temporal lobectomy. Interictal HIPDM-SPECT demonstrated decreased regional cerebral perfusion (rCP) in the epileptogenic area in only one patient, but ictal studies showed increased rCP in the epileptic foci of all three patients. In the fourth patient, interictal HIPDM-SPECT showed increased rCP in the area of epileptogenic focus; when antiepileptic medication was taken, rCP decreased. HIPDM-SPECT brain imaging is useful for localizing epileptogenic foci in CPS.
B I Lee; O N Markand; A R Siddiqui; H M Park; B Mock; H H Wellman; R M Worth; M K Edwards
Related Documents :
9098207 - Spect imaging of normal subjects with technetium-99m-hmpao and technetium-99m-ecd.
24598017 - Fabrication of multifunctional layer-by-layer nanocapsules toward the design of theragn...
11152787 - Acute pyelonephritis: comparison of diagnosis with 99mtc-dmsa, spect, spiral ct, mr ima...
11076337 - Changes in cerebral blood flow associated with premenstrual syndrome: a preliminary study.
8690607 - Alternative methods of obtaining the computed tomography dose index.
6600547 - High-resolution ct analysis of facial struts in trauma: 1. normal anatomy.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  36     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-11-21     Completed Date:  1986-11-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1471-7     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Brain / radionuclide imaging*
Cerebrovascular Circulation
Epilepsy, Temporal Lobe / radionuclide imaging*
Iodobenzenes / diagnostic use*
Tomography, Emission-Computed*
Reg. No./Substance:
0/Iodobenzenes; 84718-97-8/N,N,N'-trimethyl-N'-(2-hydroxy-3-methyl-5-iodobenzyl)-1,3-propanediamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Variability and functional recovery in the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of par...
Next Document:  Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity...